Medicinal Products

DEXTROPROPOX / PARACET / CAF RATIO 27 mg / 400 mg / 30 mg

Propofan Generic Drug
Therapeutic class: Analgesics
active ingredients: Dextropropoxyphene, Paracetamol, Caffeine
laboratory: Ratiopharm

Box of 20
All forms


Symptomatic treatment of pain of moderate to intense intensity, or not responding to the use of peripheral analgesics alone.

Dosage DEXTROPROPOX / PARACET / CAF RATIO 27 mg / 400 mg / 30 mg Tablet Box of 20

Oral way.
Reserved for adults and adolescents from 15 years old.
- The tablets should be swallowed as is, with a large glass of water, during a meal.
- 1 to 2 tablets per dose. On average 4 tablets a day divided into 2 to 4 doses.
- Do not exceed 6 tablets a day.
- The catches must be spaced at least 4 hours apart, at best 8 to 12 hours.
- In case of severe renal insufficiency (creatinine clearance less than 10 ml / min), the interval between 2 doses will be at least 8 hours.

Against indications

This medicine is contraindicated in the following situations:
- allergy to paracetamol, dextropropoxyphene or any other component of the drug,
- hepatocellular insufficiency,
- severe renal insufficiency,
- children under 15,
breastfeeding: this medication passes into breast milk; some cases of hypotonia and respiratory pauses have been reported in infants after ingestion by mothers of dextropropoxyphene at therapeutic doses. If you are breastfeeding, taking this medicine is contraindicated,
- combination with buprenorphine, nalbuphine and pentazocine (see section on interactions).
Associations advised against : alcohol, carbamazepine, enoxacin.

Dextropropox / Paracet / Caf Ratio side effects

- Few cases of hypersensitivity reactions such as anaphylactic shock, angioedema, erythema, urticaria, skin rash have been reported. Their occurrence requires the definitive discontinuation of this drug and related drugs.
- Very exceptional cases of thrombocytopenia, leukopenia and neutropenia have been reported.
- The most common: nausea, vomiting.
- More rarely: constipation, abdominal pain, rash, headache, asthenia, euphoria, minor vision disorders, disorientation, somnolence, dizziness, severe hypoglycemia, cholestatic or mixed hepatitis.
- rare cases of insomnia,
- possibility of palpitations.

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