Medicinal Products


Generic drug of Xanax
Therapeutic Class: Neurology-Psychiatry
active ingredients: Alprazolam
laboratory: Sandoz

Tablet breackable
Box of 30
All forms


- Reaction anxiety, particularly adjustment disorders with anxious mood and post-traumatic anxiety.
- Adjunctive treatment of anxiety during neuroses (including hysteria, hypochondria, phobia).
- Anxiety associated with a severe or painful somatic condition.
- Generalized anxiety.
- Anxiety attack.
- Prevention and treatment of delirium tremens.
- Alcoholic withdrawal.
Panic disorder is not an indication.

Dosage ALPRAZOLAM GNR 0.25 mg Breakable tablet Box of 30

In all cases, treatment will be initiated at the lowest effective dose and the maximum dose of 4 mg / day will not be exceeded.
The dosage of 0.25 mg is more particularly adapted to the elderly subject.
The tablet is not a form suitable for children under 6 years (risk of mis-driving).
- In current practice:
In adults, on the first day, the dosage is:
. 1 tablet at 0.25 mg in the morning,
. 1 tablet at 0.25 mg at noon,
. 1 to 2 tablets at 0.25 mg in the evening.
It must then be adapted individually according to the therapeutic response.
The average dosage is between 1 and 2 mg per day.
. In children, the elderly, the renal or hepatic insufficiency: it is recommended to reduce the dosage, for example half the average dosage may be sufficient.
- Duration of the treatment :
The treatment should be as short as possible. The indication will be reviewed regularly especially in the absence of symptoms. The overall duration of treatment should not exceed 8 to 12 weeks for the majority of patients, including the dose reduction period (see warnings).
In some cases, it may be necessary to prolong the treatment beyond the recommended periods. This requires accurate and repeated assessments of the patient's condition.
. Reactive Anxiety, Adjunctive Therapy for Neurotic Anxiety, Anxiety Associated with a Severe or Painful Somatic Condition: 4 to 12 weeks, including the period of decreased dosage.
. Generalized anxiety: long-term treatment after expert opinion.
. Anxiety attack: brief treatment.
. Prevention and treatment of delirium tremens: a few days.
. Alcohol withdrawal: treatment of 3 to 6 weeks around weaning.
- Methods of stopping treatment:
Stopping treatment should be progressive with decreasing dosage over several weeks (see precautions for use).

Against indications

This medicine should never be used in the following situations:
- hypersensitivity to benzodiazepines;
- severe respiratory failure;
- sleep apnea syndrome ;
- severe hepatic insufficiency (risk of encephalopathy).
Due to the presence of lactose, this drug is contraindicated in cases of congenital galactosemia, glucose-galactose malabsorption syndrome or lactase deficiency.
The tablet is not a form suitable for children under 6 years (risk of mis-driving).
- This medicine is generally not recommended in the following situations:
. Myasthenia gravis (see precautions for use),
. Breast-feeding: The administration of benzodiazepines causes sedative effects (lethargy, decreased tone) in children. Therefore, if taking this medicine appears essential, breastfeeding should be avoided,
. As well as in association with alcohol.
- Pregnancy: Studies in animals have shown a teratogenic effect for some benzodiazepines. Clinically, a malformation risk was mentioned for some of them, but not confirmed as a result of epidemiological studies. As a result, benzodiazepines will only be prescribed during the first trimester of pregnancy if necessary.

Adverse effects Alprazolam Gnr

They are related to the dose ingested and the individual sensitivity of the patient:
- blackouts,
- asthenia, decreased alertness, drowsiness (particularly in the elderly),
- muscular hypotonia.
- anterograde amnesia (see warnings: amnesic automatic acts),
- paradoxical reactions (see warnings) in some subjects (especially children and elderly): irritability, aggressiveness, tension, agitation, behavioral disturbances, changes in consciousness,
- physical and psychological dependence, even in therapeutic doses (see warnings) with withdrawal syndrome or rebound at the end of treatment,
- rashes, itchy or otherwise,
- changes in libido.

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