Medicinal Products


Generic drug of Xanax
Therapeutic Class: Neurology-Psychiatry
active ingredients: Alprazolam
laboratory: Evolupharm

Tablet breackable
Box of 30
All forms


· Symptomatic treatment of severe and / or disabling anxiety

· Prevention and treatment of delirium tremens and other manifestations of alcohol withdrawal.

Dosage ALPRAZOLAM EVOLUGEN 0.5 mg scored tablet Box of 30

Reserved for adults.

Oral way.


In all cases, treatment will be initiated at the lowest effective dose and the maximum dose of 4 mg / day will not be exceeded.

In general, in adults, treatment will be started at the dosage of 0.75 mg to 1 mg per day, divided into 3 doses as follows:

· 0.25 mg in the morning and at noon, and 0.25 to 0.50 mg in the evening.

The dosage will then be individually adapted according to the therapeutic response.

The average dosage is between 1 and 2 mg per day.

In the elderly, the renal or hepatic insufficiency: it is recommended to reduce the dosage, half for example. The 0.25 mg dosage is more particularly suitable in these cases.


The treatment should be as short as possible. The indication will be reviewed regularly especially in the absence of symptoms. The overall duration of treatment should not exceed 8 to 12 weeks for the majority of patients, including the dose reduction period (see Warnings and Precautions section ).

In some cases, it may be necessary to prolong the treatment beyond the recommended periods. This requires accurate and repeated assessments of the patient's condition.

Prevention and treatment of delirium tremens and other manifestations of alcohol withdrawal: short treatment of the order of 8 to 10 days.

Against indications

This medicine should never be used in the following situations:

Hypersensitivity to the active substance or any of the other ingredients,

· Severe respiratory failure,

· sleep apnea syndrome,

· Severe hepatic insufficiency, acute or chronic (risk of encephalopathy),


Adverse effects Alprazolam Evolugen

They are related to the dose ingested, the individual sensitivity of the patient.

Neuropsychiatric side effects ( see Warnings and precautions for use section )

· Anterograde amnesia, which can occur at therapeutic doses, the risk increasing in proportion to the dose,

· Behavior disorders, changes in consciousness, irritability, aggression, agitation,

· Physical and mental dependence, even at therapeutic doses with withdrawal syndrome or rebound at discontinuation of treatment,

· Lightheadedness, headache, ataxia,

Confusion, decreased alertness or drowsiness (particularly in the elderly), insomnia, nightmares, tension,

· Changes in libido.

Cutaneous adverse effects

· Skin rash, itchy or otherwise.

General side effects

· Muscular hypotonia, asthenia.

Ocular adverse effects

· Diplopia.

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