Generic drug of Almogran
Therapeutic Class: Neurology-Psychiatry
Active ingredients: Almotriptan
laboratory: EG Labo
box of 12
All forms
Indication
Treatment of the cephalalgic phase of the migraine attack with or without aura.
Dosage ALMOTRIPTAN EG 125 mg film-coated tablet box of 12
Treatment of the cephalalgic phase of the migraine attack with or without aura.
Against indications
Hypersensitivity to almotriptan or to any of the excipients listed under section Composition .
As with other 5-hydroxytryptamine (5HT1B / 1D) receptor agonists, almotriptan should not be used in patients with history, symptoms, or signs of ischemic heart disease (myocardial infarction, chest, documented silent ischemia, Prinzmetal's angina) or with severe hypertension or benign or moderate uncontrolled hypertension.
Almotriptan should not be used in patients with a history of stroke or transient ischemic attack (TIA) or in patients with peripheral vascular disease.
Concomitant administration of almotriptan with ergotamine, ergotamine derivatives (including methysergide) or other 5-hydroxytryptamine (5HT1B / 1D) receptor agonists is contraindicated.
Administration of almotriptan is contraindicated in patients with severe hepatic impairment (see also section Posology and method of administration ).
Adverse effects Almotriptan Eg
Almotriptan has been evaluated in more than 2700 patients in clinical trials up to one year. The most common adverse reactions at the therapeutic dose were: dizziness, drowsiness, nausea, vomiting and fatigue. None of these adverse events occurred at a frequency above 1.5%.
The list below shows the adverse effects that have occurred in patients during clinical trials or after marketing.
These adverse effects are presented by organ system and decreasing order of frequency.
Frequencies are defined as follows: very common (³ 1/10), frequent (³ 1/100 - <1/10), infrequent (³ 1/1000 - <1/100), rare (³ 1 / 10000 - <1/1000), very rare (<1/10000), not known (can not be estimated with available data).
Class organ system | frequent | Uncommon | Very rare | indeterminate |
Immune system | Hypersensitivity reactions (including angioedema) Anaphylactic reactions | |||
Central nervous system | Dizziness, Sleepiness | Paraesthesia, Headache | convulsions | |
Eye disorders | Visual impairment * Blurry vision* | |||
Auditory and vestibular apparatus | tinnitus | |||
Cardiovascular system | Palpitations. | Vasospasm of the coronary arteries. Myocardial infarction. Tachycardia. | ||
Respiratory system, thorax and mediastinum | Feeling of tight throat. | |||
Digestive system | Nausea Vomiting | Diarrhea, Dyspepsia, Dryness of the mouth. | ||
Musculoskeletal system, connective tissue | myalgia Bone pain. | |||
General disorders | Tired | Asthenia Pain in the chest. |
* However, visual disturbances can also occur during the migraine attack itself
Reporting of suspected adverse reactions
The reporting of suspected adverse reactions after authorization of the drug is important. It allows continuous monitoring of the benefit / risk ratio of the drug. Health professionals declare any suspected adverse reaction via the national reporting system: National Agency for the Safety of Medicines and Health Products (ANSM) and the network of Regional Pharmacovigilance Centers - Website: www.ansm.sante.fr.