Medicinal Products


Generic drug of the therapeutic class: Allergology
Active ingredients: Adrenaline
laboratory: Aguettant

Injectable solution
Box of 10 ampoules of 1 mL
All forms


- Treatment of cardiovascular arrest.
- Treatment of anaphylactic shock.
- Treatment of cardiocirculatory distress with anaphylactic shock, hemorrhagic, traumatic, infectious or secondary to cardiac surgery.
In life-threatening situations adrenaline may be used, even in sulphite-sensitive patients.

Dosage ADRENALINE AGUETTANT 1 mg / 1 mL Solution for injection Box of 10 ampoules of 1 mL

- Treatment of cardiocirculatory arrest: intravenous bolus administration of 1 to 5 mg until recovery of the hemodynamic state.
- Treatment of established anaphylactic shock:
. dilution of the 1 ml ampoule in 10 ml of physiological saline followed by bolus intravenous administration of 1 ml of the diluted solution, ie 0.1 mg of adrenaline. The boluses will be repeated until the haemodynamic state is restored. Close supervision will be established.
. or subcutaneous administration of 0.3 ml of the solution (undiluted) or 0.3 mg of adrenaline. The improvement usually occurs within 3 to 5 minutes after the subcutaneous injection. A second injection of 0.3 ml of the solution (undiluted) can be made 10 to 15 minutes later if necessary.
The doses will be in children, subcutaneously:
. less than 2 years (up to 12 kg) : 0.05 to 0.1 ml of the solution (undiluted), ie 0.05 to 0.1 mg of adrenaline,
. from 2 to 6 years (12 to 18 kg) : 0.15 ml of the solution (undiluted) or 0.15 mg of adrenaline,
. 6 to 12 years (18 to 33 kg) : 0.2 ml of the solution (undiluted) or 0.2 mg of adrenaline.
Treatment of cardiocirculatory distress with shock conditions: administration to the electric syringe continuously of a dose of between 0.01 microgram / kg / minute and 0.5 microgram / kg / minute, the average dosage being titrated according to the desired therapeutic effect.

Against indications

This medicine should never be used in case of:
- rhythm disorders (especially ventricular),
- obstructive cardiomyopathy.
This drug is generally not recommended for coronary heart failure, in combination with volatile halogenated anesthetics, imipramine antidepressants, serotonergic-noradrenergic antidepressants (milnacipran, venlafaxine), and guanethidine and related antidepressants (see interactions).

Adrenaline Aguettant Adverse Effects

- Angina attacks.
- Risk of acute myocardial infarction.
- Sinus tachycardia greater than 130 / min.
- Particularly ventricular rhythm disorders with risk of ventricular fibrillation.
- Due to the presence of sodium sulfite, risk of allergic reactions, including anaphylactic reactions and bronchospasm.

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