Medicinal Products


Generic drug from Sectral
Therapeutic class: Cardiology and angiology
active ingredients: Acebutolol
laboratory: Cristers

Coated tablet
Box of 30
All forms


· Hypertension

· Prophylaxis of stress angina attacks

· Treatment of certain rhythm disorders: supraventricular (tachycardias, flutters and atrial fibrillations, junctional tachycardias) or ventricular (ventricular extrasystoles, ventricular tachycardias).

Dosage ACEBUTOLOL CRISTERS 400 mg Film-coated tablet Box of 30

Hypertension : The usual daily dose of acebutolol is 400 mg, which should be administered either in one single dose each morning or in two doses, one in the morning and one in the evening (there is a dosage of 200 mg). mg).

This dosage may be increased in case of severe arterial hypertension.

Prophylaxis of exercise angina attacks, tachyarrhythmias : the daily dose can vary from 400 to 800 mg (600 mg on average), starting with the lowest dose and adapting, step by step, the dose to the patient. clinical condition or electrocardiogram.

Against indications

This medicine MUST NEVER be used in the following cases:

· Asthma and obstructive chronic bronchopneumopathies, in their severe forms.

· Heart failure not controlled by treatment.

· Cardiogenic shock.

· Non-paired second and third degree atrioventricular blocks.

· Angor of Prinzmetal (in pure forms and monotherapy).

· Sinus disease (including sinoatrial block).

· Bradycardia (<45-50 beats per minute).

· Phenomenon of Raynaud and peripheral arterial disorders, in their severe forms.

· Untreated pheochromocytoma.

· Hypotension.

· Hypersensitivity to acebutolol.

· History of anaphylactic reaction.

· Breastfeeding

· Combination with floctafenine (see section Interactions with other medicinal products and other forms of interaction ).

Adverse effects Acebutolol Cristers


The most frequently reported:

· Asthenia,

· Cooling of the ends,

· Bradycardia, severe if any,

· Digestive disorders (gastralgia, nausea, vomiting),

· incapacity.

Much less often :

· Slowing of atrioventricular conduction or intensification of an existing atrioventricular block,

· heart failure,

· Blood pressure drop,

· Bronchospasm,

· Hypoglycemia,

· Raynaud's syndrome,

· Aggravation of an existing intermittent claudication,

· Various skin manifestations including psoriasiform rash, or exacerbation of psoriasis (see Warnings and Precautions ).

Exceptionally :

· Pneumonitis of immunoallergic origin.


In rare cases, it has been possible to observe the appearance of antinuclear antibodies which only exceptionally accompany clinical manifestations such as lupus syndrome and cede at the end of treatment.

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